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Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 416-420 doi: 10.1007/s11684-012-0224-4
Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acutelymphoblastic leukemia (B-ALL).phenotype that resembles early T-cell precursor, which confers a much poorer prognosis than any otherThis novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL).Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblastic
Keywords: acute lymphoblastic leukemia early T precursor prognosis
Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 442-458 doi: 10.1007/s11684-021-0877-y
Keywords: T-cell acute lymphoblastic leukemia HDAC inhibitor chidamide NOTCH1 MYC ubiquitination
Precision medicine in acute lymphoblastic leukemia
Ching-Hon Pui
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 689-700 doi: 10.1007/s11684-020-0759-8
Keywords: acute lymphoblastic leukemia molecular therapeutics targeted therapy tyrosine kinase inhibitors immunotherapy CAR T-cell therapy
Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 139-149 doi: 10.1007/s11684-021-0835-8
Keywords: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 518-526 doi: 10.1007/s11684-022-0958-6
Keywords: acute lymphoblastic leukemia child venous thromboembolism epidemiology clinical characteristic risk
Chimeric antigen receptor T cell therapies for acute myeloid leukemia
Bin Gu, Jianhong Chu, Depei Wu
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 701-710 doi: 10.1007/s11684-020-0763-z
Keywords: acute myeloid leukemia CAR T immunotherapy
Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia
Ching-Hon Pui
Frontiers of Medicine 2015, Volume 9, Issue 1, Pages 1-9 doi: 10.1007/s11684-015-0381-3
With the cure rate of childhood acute lymphoblastic leukemia (ALL) approaching 90%, further improvementpatients will require better understanding of the mechanisms of drug resistance, identifying new leukemic cellDeeper characterization of leukemic cell genetic abnormalities has discovered new subtypes of leukemiasuch as early T-cell precursor ALL and Philadelphia chromosome-like ALL, and identified many genomic
Keywords: pharmacogenomics acute lymphoblastic leukemia genomics pharmacogenetics
CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies
Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 783-804 doi: 10.1007/s11684-021-0904-z
Keywords: CAR T cells hematological malignancies review
Wen Xue,Yan Sheng,Xiangqin Weng,Yongmei Zhu,Yan Zhao,Pengpeng Xu,Xiaochun Fei,Xiaoyan Chen,Li Wang,Weili Zhao
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 468-477 doi: 10.1007/s11684-015-0419-6
Mature T-cell lymphoid malignancies comprise a group of heterogeneous diseases that vary in clinicopathologicalBone marrow (BM) infiltration is more commonly present in mature T-cell lymphoid malignancies comparedthis study, clinical characteristics and prognostic factors were analyzed in 225 patients with mature T-cellThese included 29 cases of T-cell lymphoproliferative disorders (T-LPD, all with BM infiltration) andconclusion, clinical characteristics may be useful in more effectively stratifying patients with mature T-cell
Keywords: mature T-cell lymphoid malignancies clonal T-cell population bone marrow infiltration prognostic factors
Yifei Cheng,Yuhong Chen,Chenhua Yan,Yu Wang,Xiangyu Zhao,Yao Chen,Wei Han,Lanping Xu,Xiaohui Zhang,Kaiyan Liu,Shasha Wang,Lungji Chang,Lei Xiao,Xiaojun Huang
Engineering 2019, Volume 5, Issue 1, Pages 150-155 doi: 10.1016/j.eng.2018.12.006
Keywords: Donor-derived CD19-targeted T cell infusion Hematopoietic stem cell transplantation B cell acute lymphoblasticleukemia Minimal residual disease
Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 229-238 doi: 10.1007/s11684-017-0506-y
A CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group foradult acute lymphoblastic leukemia (ALL).Fifty-eight (36 with haploidentical donor) patients underwent allogeneic hematopoietic stem cell transplantation
Keywords: Philadelphia chromosome acute lymphoblastic leukemia imatinib CALLG2008
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 711-725 doi: 10.1007/s11684-020-0808-3
Keywords: chimeric antigen receptor T (CAR-T) cell lymphoma cytokine release syndrome (CRS) immune effector cell-associated
Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection
Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 746-751 doi: 10.1007/s11684-020-0822-5
Keywords: SARS-CoV-2 neutralizing antibodies T-cell response
ZHU Lidong, CHEN Xiaoping
Frontiers of Medicine 2007, Volume 1, Issue 4, Pages 364-368 doi: 10.1007/s11684-007-0070-y
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 347-371 doi: 10.1007/s11684-020-0821-6
Keywords: BCP-ALL subtypes translocation aneuploidy sequence mutations
Title Author Date Type Operation
Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen
Journal Article
Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia
Journal Article
and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cellacute lymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia
Journal Article
Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese
Journal Article
Chimeric antigen receptor T cell therapies for acute myeloid leukemia
Bin Gu, Jianhong Chu, Depei Wu
Journal Article
Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia
Ching-Hon Pui
Journal Article
CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies
Journal Article
Clinical characteristics and prognostic factors of patients with mature T-cell lymphoid malignancies:
Wen Xue,Yan Sheng,Xiangqin Weng,Yongmei Zhu,Yan Zhao,Pengpeng Xu,Xiaochun Fei,Xiaoyan Chen,Li Wang,Weili Zhao
Journal Article
Donor-Derived CD19-Targeted T Cell Infusion Eliminates B Cell Acute Lymphoblastic Leukemia Minimal ResidualDisease with No Response to Donor Lymphocytes after Allogeneic Hematopoietic Stem Cell Transplantation
Yifei Cheng,Yuhong Chen,Chenhua Yan,Yu Wang,Xiangyu Zhao,Yao Chen,Wei Han,Lanping Xu,Xiaohui Zhang,Kaiyan Liu,Shasha Wang,Lungji Chang,Lei Xiao,Xiaojun Huang
Journal Article
imatinib plus CALLG2008 protocol in adult patients with newly diagnosed Philadelphia chromosome-positive acutelymphoblastic leukemia
Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin
Journal Article
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Journal Article
Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection
Yun Tan, Feng Liu, Xiaoguang Xu, Yun Ling, Weijin Huang, Mingquan Guo, Ziyu Fu, Dongguo Liang, Miao Xu, Hongzhou Lu, Saijuan Chen
Journal Article
Change and significance of T-cell subsets and TNF-α in patients with advanced malignant obstructive jaundice
ZHU Lidong, CHEN Xiaoping
Journal Article